In a flashback to the 1960s, Anna arrives in San Francisco, befriends some trans women and starts dating a man. But she soon finds her loyalties tested.

Maggie and OA lead the search for an abducted former biological weapons chemist.

Former Marine Frank Castle takes the law into his own hands while struggling to come to terms with his traumatic past.

Jo and Henry pursue the killer of a jewelry store burglar who has a connection with Jo’s dead husband.

As the team tries to protect a target of the Pavlovich brothers — specialists in abductions — Red has a job of his own for the duo; Liz patiently pursues…

Shaw and Riley investigate the death of a therapist with a long list of troubled clients. Baxter takes over Price’s chair when a disturbing connection to the defendant is discovered.