As Dante navigates a painful new normal, Sam embraces a thrilling opportunity. Annette works to master — and maintain — the rhythm of her life.

Halstead and Cuevas struggle to diagnose a patient with a rare disorder. CFD and Med staff work to free a paranoid father trapped in the MRI suite. Tanaka-Reed gets an…

Dr. Song launches her pilot program, giving the E.D. a technological facelift. Archer clashes with Charles on a patient faking paralysis. Archer helps a pregnant mother with a heart condition.

Maggie clashes with Charles over a distrustful patient. Marcel and Halstead fight against Med’s new policies. Asher and Archer pull surprising things out of their unsuspecting patients.

Marcel and Charles treat Lieu’s gym buddy. Maggie and Halstead help a robbery-homicide suspect. Asher and Archer use Med’s new opiate abuse AI program.

A brutal storm rocks Chicago. Halstead encourages Dr. Grace Song to go against her own findings for the benefit of their patient. Asher rushes to the hospital to help Archer’s…

Halstead and Marcel facilitate a trans-organ exchange. Asher and Cuevas help a sexual assault survivor. Choi and Archer treat a patient whose case could expose a fraudulent doctor.

Scott and Archer diagnose a pregnant woman with a serious infection. Maggie receives shocking news. Halstead and Charles question an elderly patient’s Alzheimer’s diagnosis. In an effort to help a…

Halstead helps a patient with long-haul COVID-19 symptoms. Taylor reflects on her dating life when she learns that a patient’s daughter is having an arranged marriage.

Rival gangs bring their war to Med. Halstead and Charles work with a brain cancer patient who’s refusing treatment. Tensions run high in the OR when a patient’s transplanted uterus…

Caroline has news to share, forcing Dr. Charles to make a serious decision about their relationship. Maggie meets her sister’s new boyfriend, but discovers danger may lie ahead. Dr. Rhodes…

Vanessa and Archer disagree on how to handle the victim of a motorcycle accident. Dylan and Charles deal with a UNICEF negotiator with repressed trauma. Stevie and Will treat a…

April finds herself in a dangerous situation and Natalie gets an update on Will. Dr. Rhodes gears up for a gala honoring his hybrid O.R. and tries to convince Dr….

Halstead hides the theft of his gun from a suspicious Manning. Tensions are still high between Connor and Bekker, who take a risk operating on an HIV-positive patient. Hank breaks…

Dr. Manning and Dr. Halstead become skeptical of a patient’s injuries when the victim of a car accident is brought into the hospital. Ethan and April have a difficult time…

The doctors and nurses of Chicago Med find themselves on high alert when an overflow of patients are rushed into the doors following a terrifying apartment complex blaze. Dr. Rhodes…

Dr. Halstead gets an unplanned visit from the CPD while Ethan is skeptical of a woman who is experiencing chronic pain. Natalie tends to a cancer patient whose brother has…

When things become complicated, Will is forced to lie to Natalie. Ethan and April find out some compromising information about Emily’s boyfriend and Ava is unsure of what to do…

Dr. Manning and Dr. Charles treat a teenage girl with a rapidly changing set of symptoms that has everyone perplexed. Dr. Choi and medical student Jeff Clark encounter a 19…

Chicago Med braces for an influx of trauma patients when a pre-dawn pileup finds the hospital in full scramble mode. As a result of the storm and emergencies, supplies become…

It’s a miracle when a trauma patient survives the trip to the hospital, putting the pressure on Dr. Rhodes to keep the man alive. Dr. Choi and Dr. Manning have…

After witnessing a drive-by shooting and hitting her head, Dr. Manning struggles with the aftermath of a head injury. Complicating matters, she and Dr. Halstead deal with a teenage patient…

Dr. Manning and Dr. Rhodes separately treat complicated cases involving sick babies, only to uncover that the two cases could actually be intertwined. Elsewhere, Dr. Halstead and Dr. Charles treat…

Nurse Lockwood gets arrested when she takes a stand. Meanwhile, Dr. Halstead deals with a pending lawsuit against him; a baby’s injuries come into question; Dr. Charles faces personal issues;…

An erratic patient arrives, claiming that his heart is pounding inside his head as he takes drastic measures to stop it. Also, Dr. Manning helps a boy with a broken…

Dr. Rhodes and Dr. Downey clash over how to treat a patient with various health and heart issues. Meanwhile, excessive hoarding at a home comes into play when trying to…

The grand opening of Chicago Med’s emergency department is interrupted by victims of an elevated train crash, pushing the staff to their limits.

Casey reconsiders his run for alderman after he’s targeted by a propaganda campaign. The squad responds when a man is trapped inside of a burning car. Trudy’s nerdy brother plans…

Lt. Casey is unable to rescue a woman who becomes trapped inside her burning greystone, prompting him and Lt. Severide to butt heads over the husband’s role in the tragedy….