Returning to Florence, an uninspired Leonardo accepts to paint the portrait that will become the Mona Lisa; after failing to repair his relationship with Caterina, Leonardo goes to Imola, where…

In Milan, in 1506, Leonardo da Vinci is arrested on charges of having poisoned Caterina da Cremona. After declaring his innocence to Stefano Giraldi, an official of the Podestà, Leonardo…