While Sarah embarks on a wilderness adventure, Charlie and Rex investigate the murder of a college professor.

When local radio therapist, Dr. Rohan Love, starts acting strangely and spending huge sums of money, his wife Meera hires Shade and Angie to find out what secret he’s hiding.

Nandor’s old familiar from the 1970s returns to Staten Island, Guillermo leaves to serve a new master, and Nadja and Lazslo revive their musical act.

When a bomb goes off in Washington D.C., the team suspects an innocent man is being framed for the crime. Meanwhile, Kilroy tracks down a notorious hacker.