Nellie takes a swing at spontaneous romance. Joanna reconsiders the minor perks — and major pitfalls — of chasing passion.

Third-year med students begin their rotation in the ED and Maggie keeps a careful eye on one of them. Natalie, whose mom’s health takes another decline, tries to cover up…

In the aftermath of Halstead’s apartment fire, Marcel, Choi and Archer work together to try to save the survivors. Charles and Med’s new fellow, Cuevas, help a paranoid patient.

The Smutnys receive unexpected guests, Josto and Gaetano reunite, Loy challenges the status quo and Oraetta is caught.

Deafy and Odis join forces, Josto seeks revenge, Oraetta finds new employment, Gaetano makes a move and Zelmare and Swanee help the Smutnys with their debt.