The BAU is called to upstate New York to investigate mysterious disappearances. Also, Prentiss gets some disturbing news about one of her former Interpol colleagues.

The residents are on their own with the dreaded night shifts while the attendings go out to play to celebrate Derek’s grant for his clinical trial.

Sanjay has a new experience. Nancy gets bruised. Conrad won’t do what U-Turn wants him to. Lupita still won’t follow orders. Heylia’s out to handle a few things. The Amber…