Just when the ER is understaffed and swamped, two children who were brought in turn out to have full blown smallpox. The entire ER must be locked down. The staff…

Dr. Carter, Abby and other staff of the ER are quarantined as the CDC investigate a mysterious, deadly outbreak.

Liz’s grandmother is rushed to the hospital after suffering a stroke prompting Liz to reach out to Max for comfort.