Sam and Kelly investigate a ketamine theft at an animal sanctuary as Naz and Nathan work to catch the dealer of a dangerous new synthetic drug.

A surge in gun violence in a community undergoing gentrification brings Sam and Kelly to a Caribana mas camp. Tensions rise when a shooting leaves them searching for those responsible.

When Officer Maya Power and her K9 partner Rebel are violently attacked responding to a call about a warehouse break-in, Major Crimes is at the ready.

Jett tracks down Frank Sweeney, a brutal gangster she and Blair worked for ten years earlier.