When a young woman with HIV symptoms and no insurance refuses to take the test, Goodwin and Dr. Choi attempt to treat her without taking a toll on the hospital’s…

Ethan attempts to diagnose a man with no symptoms while Sarah’s paranoia goes to the extreme when she uses pepper spray on an aggressive patient. Will treats a young couple…

Dr. Charles feels pressure when Dr. Choi and Dr. Manning criticize his medical decision regarding an ill newborn baby. Dr. Rhodes comes to terms with his relationship issues. Goodwin helps…

Sunny works with the River King to secure passage to Pilgrim’s Fortress. The Widow faces mutiny from discontented troops.

Supergirl and team take on Selena in an epic battle for Earth.

Sunny and Bajie arrive at Pilgrim’s Fortress, only to face an angry M.K. The Widow enlists Gaius. Moon and Lydia rally the troops.

Sunny and Bajie go undercover on The Widow’s frontlines, seeking passage to a possible cure for Henry. Tilda confronts The Widow.

Sunny and Bajie face off against a deadly new foe with a dark connection to Sunny’s past. Chau enlists her brother in the fight against Pilgrim.

Sunny and Bajie seek help from a reclusive former Master. The Widow must confront a spectre from her past as Chau’s slave.

Supergirl learns the true depth of Serena’s nefarious plans for Earth. Supergirl, Mon-El and Alura must devise a plan to stop her before Serena gets to Earth. J’onn prepares to…

Sunny and Bajie call in a favor from Bajie’s past. The Widow interrogates an important captive who threatens her tentative peace with Pilgrim.

When Winn’s father dies, his estranged mother, Mary, reappears trying to reconnect and to explain why she abandoned him all those years ago. Winn is too embittered from his rough…

Myr’nn inadvertently causes psychic disturbances at the DEO; Supergirl must work with J’onn to contain the chaos; Mon-El begins training Kara in fighting techniques he’s learned in the future.

Supergirl and Imra have different ideas on how to stop the third Worldkiller, Pestilence. However, when both Alex and Winn are seriously injured by Pestilence, Supergirl and Imra team up…

Still reeling after learning about Lena’s secret, Supergirl asks Guardian for a favor that could alter his relationship with Lena forever. Meanwhile, with all three Worldkillers united, Supergirl and the…

When Reign starts hunting Ruby, Supergirl and Alex work together to keep her safe. Supergirl and J’onn look to Sam’s mother for advice on how to stop Reign and come…

When Tanya, a disciple of Coville’s, escapes from what’s left of his cult, she gives Kara and James a journal that could hold the key to saving Sam. Someone learns…

Supergirl is stunned to discover that a part of Krypton survived. Meanwhile, Alex is attacked while out with Ruby, and Lena considers how far she will go to keep Reign…

Sunny returns to the Badlands, seeking a cure for his son Henry. The Widow and Chau wage a bloody civil war. A new threat emerges.

Sunny and Bajie seek help from Lydia. The Widow struggles to control M.K. Pilgrim seeks to establish a new order in the Badlands.

Kara makes a major life decision. Meanwhile, J’onn finds out that special DEO-caliber guns have hit the streets of National City.

The DEO captures a second Worldkiller, Purity. Supergirl and Alex use very different methods of interrogation with Purity in the hopes of finding out how to defeat Reign. However, Purity…

Struggling to heal from her injuries inflicted by Reign, Supergirl remains in a dreamlike state, unable to be reached. Mon-El recruits one of the Legion members, Brainiac-5, to try to…

As Reign continues to terrorize the city, Supergirl teams up with Saturn Girl, and the two recruit Supergirl’s former enemies, Livewire and Psi, to form a team for a mission…

Someone tries to kill Morgan Edge and he barely survives. He accuses Lena of being behind the attempt and vows to destroy her. When Lena fears her hatred for Morgan…

When Supergirl needs help, Alex asks Lena and Brainiac to team up. Meanwhile, J’onn questions his decision to quit the DEO. However, after running into Manchester Black, he realizes there…

Colonel Haley makes a surprising decision regarding Supergirl. Kara writes a series of articles highlighting aliens in National City in the hopes that humans will stop being so fearful of…

Everyone gathers for Thanksgiving but Kara is feeling down after her televised debate with Ben Lockwood about the anti-alien sentiment coursing through National City. Meanwhile, James and Lena argue about…

James falls in deeper with the Children of Liberty in his efforts to meet Agent Liberty. Meanwhile, Supergirl and Manchester Black follow a lead on Agent Liberty’s location, but things…

Nia has a powerful dream about Agent Liberty but refuses to look at it as a prophetic dream and pushes it aside. After noticing something is bothering Nia, Kara enlists…

Supergirl, The Flash, Green Arrow and Superman engage in the battle of their lives. The crossover starts on The Flash S05E09 Elseworlds (I) and Arrow S07E09 Elseworlds (II).

Diving back into reporting, Kara welcomes a new cub reporter to CatCo. Meanwhile, James and Lena argue about James’ impending indictment for acting as the vigilante Guardian, while Alex and…

A shocking revelation causes chaos in National City. Supergirl sets out to capture Mercy Graves, while Alex takes control at the DEO. Back at CatCo, Kara decides to write an…

Ben Lockwood didn’t always hate aliens. Through a series of incidents, and input from his anti-alien father, Ben slowly transforms from a mild-mannered professor into the villainous Agent Liberty of…

Strand and Dorie are marooned. Luciana aids a man in need. The group’s efforts to help a stranger put everyone in danger.

Difficult decisions lead the group into uncertainty. Alicia delivers on a promise to Charlie.

The group’s hope falters as they seek a way out. Alicia and Charlie reunite with friends.

Morgan struggles to find the strength to help friends in dire need before it’s too late.

Madison fights to preserve the life she worked so hard to build. Morgan tries to do the right thing.

Morgan tries to help Alicia and the fractured group of survivors as a storm brews.